Kill the tigers

Here's a choice: save the last remaining tigers on the planet, or kill them, chop them into pieces, and eat them in the mistaken belief that tiger parts can be used as medicine.

Sounds like an easy choice, no? Unfortunately, humans have already decided to kill the tigers rather than saving them. Fewer than 4,000 wild tigers survive on the planet. As journalist Caroline Alexander wrote in a compelling article in the December issue of National Geographic, "tigers in the wild face the black abyss of annihilation." And their greatest threat, she writes, is "the brutal Chinese black market for tiger parts."

Traditional Chinese Medicine (TCM) practitioners claim that tiger parts can be used to treat a wide variety of ailments, including malaria, bacterial infections, bad skin, ulcers, leprosy, and impotence. There is not a whit of scientific evidence to support any of these claims; they are nothing more than folk medicine, based on primitive beliefs dating from a pre-scientific era, when it was believed you could acquire the properties of an animal by eating it. Unfortunately, these beliefs have driven the mightiest of the big cats to the brink of extinction.

The World Federation of Chinese Medicine Societies asked its members to stop using tiger bones last year, but their action is far too little, too late. The New York Times reported around the same time that tiger-based "medicines" are widely available in China.

Proponents of Traditional Chinese Medicine claim that it is beneficial, but they have no science to back them up. NIH's National Center for Complementary and Alternative Medicine (NCCAM), an apologist for all sorts of quack medical practices, explains that

"In the TCM view, a vital energy or life force called qi circulates in the body through a system of pathways called meridians. Health is an ongoing process of maintaining balance and harmony in the circulation of qi."

This is little more than fantasy. Too bad NCCAM's leaders seem to have forgotten whatever they knew about human physiology. They might just as well explain that midi-chlorians circulating in the blood are the source of the Force. (Actually, there are midichlorians in nature now, in a species of tick.  Really.)

Some forms of "alternative medicine" are ineffective but mostly harmless (think homeopathy, which is just water and sugar pills), while others can be harmful to the patients who use them (think acupuncture, with its risk of infection, or ayurveda, which uses toxic chemicals). TCM is doubly harmful: it doesn't benefit patients, and it is the single greatest threat to the world's tigers. I hope people come to their senses before the last tiger is gone.

Does NIH recommend acupuncture?

"NIH recommends acupuncture" - that's the headline on a recent web article on an acupuncturists' website. Now, I know that NIH has granted millions of dollars to acupuncture researchers who have tried their best to prove it works, but I didn't think NIH officially endorsed it. For one thing, despite these wasted millions, the best evidence shows that acupuncture doesn't work, not even a little bit.

What the article was referring to illustrates the dangers of NIH's far-too-gentle treatment of acupuncture and other "alternative" practices. It also shows how promoters of questionable or downright bogus practices can distort the facts to suit their own ends.

What the acupuncturists found was an NIH news site that ran an article called "Understanding acupuncture: time to try it?" (Note the question mark.) The article was written by Harrison Wein, a science writer at NIH who interviewed a handful of researchers, most of them promoters of acupuncture themselves who are funded by NCCAM.

(I've written about NCCAM before, so here I'll just remind readers that it was created by Congress as a way to earmark funds for bad science that can't pass muster in normal peer review. NCCAM grants over $200 million per year to its stable of mediocre scientists.)

Wein did a very poor job of describing the complete implausibility of acupuncture, but he did at least point out that sham acupuncture works just as well as "real", and it doesn't even matter if you use toothpicks that don't pierce the skin. So does his article endorse acupuncture? In a sidebar titled "If you want to try acupuncture," it says:

• "Don’t use acupuncture as a replacement for conventional care"
• "Don’t rely on a diagnosis of disease by an acupuncturist who doesn’t have conventional medical training"

and a few similar things, none of them recommendations for acupuncture. The article concludes by asking the question again:

"Should you try acupuncture? Studies have found it to be very safe, with few side effects. If you’re thinking about it, talk to your doctor."

So no, not an endorsement. Just a much-too-gentle recommendation to talk to your doctor first. The writer (Wein) regurgitates the claims of acupuncture promoters hook, line, and sinker - and he doesn't cite any evidence for his statement that it is "very safe." In fact, acupuncture often causes infections, sometimes serious ones. And as I wrote last month in The Atlantic: in 1995, a 40-year-old Norwegian woman visited an acupuncturist for relief from fibromyalgia. As described in The Lancet, she died two hours later, and an autopsy revealed that the needle had punctured her left ventricle.

Think that's just one unfortunate anecdote? Well, in the journal BMJ last year, researchers reported that acupuncture infections are a significant problem worldwide, and that they have been under-reported for years. Infections caused by acupuncturists have led to "joint destruction, multi-organ failure, flesh-eating disease and paralysis" as well as hepatitis B and C and mycobacteriosis.

So I don't agree that acupuncture is "very safe." After I gave an interview on Minnesota Public Radio last month, I was attacked by acupuncturists claiming that they don't use "dirty needles" (which I never claimed) - but in saying this, the attackers reveal their own ignorance. Needles aren't the problem: it's that every site on the skin as well as the acupuncturists hands that need to be sterilized. You see a photo on the website of the American College of Acupuncture and Oriental Medicine of a bare-handed person inserting needles into someone's skin. In case they remove it after reading this article, here it is:

All this should be beside the point, though, because acupuncture simply doesn't work. One of the acupuncture researchers (funded by NCCAM) interviewed in the NIH news story, Karen Sherman, had this response to the data showing that toothpicks work as well as needles:

"For example, when researchers have compared inserting needles with just pressing a toothpick onto acupuncture points, they’ve often found both treatments to be successful. But Sherman questions whether these are really controls. Many traditional acupuncturists would consider them true treatments, too. The important thing, in their view, is to hit the right spot, not necessarily how deep you go."

So when the evidence doesn't show what she likes, Dr. Sherman changes the definition of placebo. This is called "moving the goalpost," and it's a classic sign of bad science (and a bad scientist). Actually, she goes even further, saying "I don’t really think you can come up with a great placebo needling." In other words, in Dr. Sherman's world, acupuncture can't really be tested. I guess it's just magic.

Even though the NIH article doesn't recommend acupuncture, it uncritically repeats some ridiculous claims, such as:

"… the body contains a delicate balance of 2 opposing and inseparable forces: yin and yang. Yin represents the cold, slow or passive principle. Yang represents the hot, excited or active principle. Health is achieved through balancing the 2. Disease comes from an imbalance that leads to a blockage in the flow of qi—the vital energy or life force thought to regulate your spiritual, emotional, mental and physical health. Acupuncture is intended to remove blockages in the flow of qi and restore and maintain health."

I want to laugh at this, but it appears on an honest-to-goodness NIH website. As my colleagues at Science-Based Medicine put it, "acupuncture is a pre-scientific superstition." It does not deserve our respect, nor should we take it seriously.

There's no scientific evidence whatsoever that "the flow of qi" has any physiological basis. The passage above should have been followed with a bit of real information, such as: "Scientifically, there is no more evidence for qi than there is for the tooth fairy or Santa Claus. However, some researchers argue that Santa Claus is quite a bit more plausible." But that would perhaps be hoping for too much backbone from NIH. Note to NIH: don't give pseudoscientists the imprimatur of legitimacy by repeating their claims. And pay better attention to what you allow on your website.

Bad medicine at the University of Maryland

Pseudoscience is insinuating itself into our medical schools across the nation, going by the name "Integrative Medicine." Integrative medicine is just the latest buzzword for a collection of superstitions, myths, and pseudoscience that has gone by various names over the years. First it was Holistic medicine, and once that fell out of favor, it became Alternative medicine, followed soon after by Complementary and Alternative medicine (CAM), and lately Integrative medicine. These names can't disguise the fact that many of the practices lumped together are bad medicine. What disturbs me particularly, as a professor, is that CAM is moving into the medical curriculum at respectable medical schools, including the University of Maryland.

Perhaps the best way to reverse this trend is to call attention to it. Academic freedom allows professors to proclaim all sorts of wild ideas, including nonsensical ones, but we don't have to allow them to teach courses with no basis in reality. That same academic freedom, incidentally, allows me to criticize bad science wherever I find it, including my own university.

So what's going on at Maryland's medical school? UMM is home to one of the nation's premier "integrative medicine" programs, which promotes a wide range of questionable practices. Its clinical services include:

• Acupuncture
• Homeopathy
• Reflexology
• Reiki
• Qi Gong

Although each of these has a different history, all of them are, well, nonsense. Let's take a closer look homeopathy, which is perhaps the most ridiculous pseudoscience on the list. Homeopathy is based on two ideas: that "like cures like", and that vanishingly small quantities of medicine are stronger than larger quantities. Both ideas were invented by Samuel Hahnemann in the late 1700s, back when most medicine was pretty bad for you. Unfortunately for Hahnemann, his ideas were no better.

The idea that "like cures like" is used to justify treating (for example) itchiness with extract of poison ivy. I'm not making this up: this is a standard homeopathic preparation, promoted on many homeopathic sites, even (sorry, cycling fans) on Lance Armstrong's Livestrong website.

The second idea is that you dilute these substances so much that instead of causing the symptom, they cure it. Alas, Hahnemann was unaware that when you dilute a substance to the degree that he recommended, you end up with nothing left. Typical dilutions used today go by the abbreviations 10C, 20C, or 30C. One "C" is a dilution of 1 in 100, and 20C means that you dilute the active ingredient 100-fold, and then repeat the process 20 times over. This is a dilution of 100 to the 20th power, a ridiculously large number. If you had a single molecule immersed on a sphere of water the size of the entire planet, it would still not be dilute enough.

That's right: homeopathic treatments are just water. Or rather, water dropped onto a sugar pill, and sold at stores such as Whole Foods, which has a section devoted to homeopathic remedies. And offered up as medicine by the University of Maryland's Center for Integrative Medicine through their clinical services. (Why isn't this malpractice? I haven't figured that out yet.)

The other treatments offered by the UMM Center are no better. Their Qi Gong brochure explains that

"sickness, pain or physical disorders are the result of qi blockage, or unbalanced qi in the body. Qigong practice helps to balance the qi system in the body and break the qi blockage(s) to recover health."

There's no scientific basis for qi - it is simply magical thinking. The brochure, though, claims that Qigong will give you "an increased resistance to illness through a stronger immune system." None of these claims have any good science to back them up.

But it gets worse. The Center for Integrative Medicine is offering lectures and courses in all four years of the medical school curriculum, and it boasts that the "integrative medicine elective has become a top choice for fourth year medical students." How unfortunate that this pseudoscience has infiltrated its way into the medical curriculum, and that the UMM Center is, in essence, mis-training medical students at one of the nation's oldest medical schools.

By providing a respectable home for these pseudoscientific practices, UM Medicine is undermining its own scientific and educational missions. But when the money is coming in, the administration seems quite happy to support it. Last August, the Dean of Medicine issued a glowing press release about the Center, after its Director published a very poor study (see my earlier blog about that one) arguing for the use of acupuncture. I don't know if the Dean believed that press release, but someone ought to tell him that Integrative Medicine has no place in a 21st century medical curriculum. I guess I just told him.

Note: why do I pick on U. Maryland? Primarily because it's my own institution (although I noted previously that UM Medicine is a separate campus from the main campus at College Park where I work). There are plenty of other Integrative Medicine programs at reputable medical schools, most of them just as deserving of criticism.